MANUFACTURING
Since its inception Apotex Pharmachem Inc. has continued to expand and refine its manufacturing capabilities to meet customer needs. State-of-the-art kilo-lab, pilot plant, and manufacturing facilities allow Apotex Pharmachem Inc. to simultaneously manufacture up to ten different active pharmaceutical ingredients. Apotex Pharmachem's facility has been
designed to ensure maximum flexibility and to carry out a wide variety of
chemistries while maintaining cGMP compliance.
Apotex Pharmachem's production facility currently consists of eleven manufacturing plants
(work centres) that have a reactor capacity range from 50 L to 5000 L, a process development kilo-lab, as well as preparative HPLC capability.
Innovation is central in our approach to Apotex Pharmachem Inc.'s production, we are adept at devising technological solutions to satisfy unique and challenging customer requirements.
Plant Capabilities
- Standard Operating Temperature Range: - 15 oC to 140 oC
- High pressure/high vacuum operating ranges
- Low & High Temperatures Capability from: –80 oC to 200 oC
- High containment procedures for potent APIs
- Solvent recovery and recycling
Apotex Pharmachem's drying and material handling areas are built to class 100,000 clean
room specifications. Four product drying technologies are currently in use:
vacuum tray, agitated vacuum pan, vacuum rotary double cone, and fluid bed. Multiple
milling and micronization technologies are also present to achieve customer’s particle size requirements.
MANUFACTURING PARTNERSHIPS
With facilities in Canada, Mexico, India and China, Apotex Pharmachem Inc. manufacturing partnerships are geographically dispersed and have been established to allow a maximum
flexibility in production capabilities.